rss
Br J Ophthalmol doi:10.1136/bjo.2007.120675

Maculopathy in uveitis of Juvenile Idiopathic Arthritis- An Optical Coherence Tomography study

  1. Ghislaine Ducos de Lahitte (ducosg{at}yahoo.fr),
  2. Celine Terrada,
  3. Laurent Kodjikian,
  4. Chau Thi Ha Tran,
  5. Nathalie Cassoux,
  6. Phuc Lehoang,
  7. Bahram Bodaghi
  1. La Pitie Salpêtrière Hospital, France
  2. La Pitie Salpêtrière Hospital, France
  3. La Croix-rousse Hospital- Lyon, France
  4. La Pitie Salpêtrière Hospital, France
  5. La Pitie Salpêtrière Hospital, France
  6. La Pitie Salpêtrière Hospital, France
  7. La Pitie Salpêtrière Hospital, France
    • Published Online First 21 June 2007

    Abstract

    Aim: To examine the frequency and characteristics of macular lesions observed in Juvenile Idiopathic Arthritis (JIA) uveitis, using Optical Coherence Tomography (OCT).

    Methods: In this cross-sectional study, 38 consecutive patients were recruited from a tertiary referral center in uveitis. All eyes with JIA uveitis underwent complete ophthalmic examination including OCT 3. Exclusion criterion was the inability to obtain OCT scans. Flare and visual acuity were also analysed by using linear regression.

    Results: We analyzed foveal thickness (FT) and central foveal thickness (CFT) using the software mapping, to describe macular lesions in 61 eyes. Maculopathy was observed in 51 eyes (84%), compared to 12% in the literature (P<0.0001) and comprised four types: perifoveolar thickening in 45 eyes (74%), macular edema in 29 eyes (48%), foveal detachment in 11 eyes (18%), and atrophic changes in 6 eyes (10%). Only 4 eyes did not demonstrate any lesion.

    Conclusions: Among children with JIA-uveitis, macular involvement is frequent, and characterized by perifoveolar thickening and serous retinal detachment. OCT is a non-invasive instrument. It may easily shows this maculopathy, which could impair visual function.

    This Article

    1. Abstract
    2. PDF
    4. All versions of this article:
      1. bjo.2007.120675v1
      2. 92/1/64most recent

    Responses

    1. Submit a response
    2. No responses published

    Register for free content

    The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

    Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.