Article Text

other Versions

PDF
Abnormal fundus autofluorescence patterns in myopic choroidal neovascularization
  1. Miki Sawa (sawamiki{at}ophthal.med.osaka-u.ac.jp),
  2. Fumi Gomi,
  3. Motokazu Tsujikawa,
  4. Yasushi Ikuno,
  5. Hirokazu Sakaguchi,
  6. Kaori Sayanagi,
  7. Yasuo Tano
  1. Department of Ophthalmology, Osaka University Medical School, Japan
  2. Department of Ophthalmology, Osaka University Medical School, Japan
  3. Department of Ophthalmology, Osaka University Medical School, Japan
  4. Department of Ophthalmology, Osaka University Medical School, Japan
  5. Department of Ophthalmology, Osaka University Medical School, Japan
  6. Department of Ophthalmology, Osaka University Medical School, Japan
  7. Department of Ophthalmology, Osaka University Medical School, Japan

    Abstract

    Background/Aims: To investigate fundus autofluorescence (FAF) findings in eyes with myopic choroidal neovascularization (CNV).

    Methods: Observational case series. Twenty-seven consecutive eyes with CNV for at least 1 year were included. We evaluated FAF patterns, time after the onset of CNV seen on FAF, and FAF changes.

    Results: We observed the following patterns. Pattern I (n=2), relative hypoautofluorescence around the CNV surrounded by hyperautofluorescence a mean of 17 months after CNV onset; pattern II (n=11), small lobular or multilobular well-defined FAF defects within a relatively hypoautofluorescent region surrounded by hyperautofluorescence a mean of 35 months after onset; pattern III (n=4), lobular or multilobular well-defined FAF defects surrounded by hyperautofluorescence a mean of 59 months after onset; and pattern IV (n=10), large lobular or crescent-shaped well-defined FAF defects a mean of 107 months after onset. Well-defined FAF defects corresponded to chorioretinal atrophy on color fundus photographs. During the follow-up period, two eyes with pattern I evolved into pattern II. Lobular or multilobular well-defined FAF defects enlarged in 11 eyes (pattern II, 9 eyes; pattern III, 2 eyes).

    Conclusion: Autofluorescent changes progress over time through pattern grading. A pattern classification might be helpful to predict chorioretinal atrophy changes around myopic CNV.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.