Background/Aims: To investigate fundus autofluorescence (FAF) findings in eyes with myopic choroidal neovascularization (CNV).
Methods: Observational case series. Twenty-seven consecutive eyes with CNV for at least 1 year were included. We evaluated FAF patterns, time after the onset of CNV seen on FAF, and FAF changes.
Results: We observed the following patterns. Pattern I (n=2), relative hypoautofluorescence around the CNV surrounded by hyperautofluorescence a mean of 17 months after CNV onset; pattern II (n=11), small lobular or multilobular well-defined FAF defects within a relatively hypoautofluorescent region surrounded by hyperautofluorescence a mean of 35 months after onset; pattern III (n=4), lobular or multilobular well-defined FAF defects surrounded by hyperautofluorescence a mean of 59 months after onset; and pattern IV (n=10), large lobular or crescent-shaped well-defined FAF defects a mean of 107 months after onset. Well-defined FAF defects corresponded to chorioretinal atrophy on color fundus photographs. During the follow-up period, two eyes with pattern I evolved into pattern II. Lobular or multilobular well-defined FAF defects enlarged in 11 eyes (pattern II, 9 eyes; pattern III, 2 eyes).
Conclusion: Autofluorescent changes progress over time through pattern grading. A pattern classification might be helpful to predict chorioretinal atrophy changes around myopic CNV.