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Br J Ophthalmol doi:10.1136/bjo.2008.139600

Fibrin glue versus sutures for conjunctival autografting in Pterygium surgery: A Prospective Comparative Study

  1. Aylin Karalezli (akaralezli{at}yahoo.com),
  2. Cem Küçükerdönmez (drcemk{at}hotmail.com),
  3. Yonca A Akova (yoncaakova{at}yahoo.com),
  4. Rana Altan-Yaycýoðlu (raltanya{at}yahoo.com),
  5. Mehmet Borazan (mborazan{at}yahoo.com)
  1. Baskent University School of Medicine, Department of Ophthalmology, Turkey
  2. Baskent University, School of Medicine, Department of Ophthalmology, Turkey
  3. Baskent University, School of Medicine, Department of Ophthalmology, Turkey
  4. Baskent University, School of Medicine, Department of Ophthalmology, Turkey
  5. Baskent University, School of Medicine, Department of Ophthalmology, Turkey
    • Published Online First 11 July 2008

    Abstract

    Aim: To compare the use of fibrin glue versus sutures for fixating conjunctival autografts in patients undergoing pterygium excision.

    Methods: Fifty patients (50 eyes) with primary pterygium were randomized to undergo pterygium surgery using either fibrin glue (25 eyes) or 8-0 Vicryl sutures (25 eyes) to attach the conjunctival autograft. The patients were followed-up for 12 months. Outcome measures were postoperative patient comfort, duration of surgery, and recurrence of pterygium.

    Results: In the fibrin glue group, the mean operation time was 15.7±2.4 minutes (range, 12-18 minutes); it was 32.5±6.7 minutes (range, 25-40 minutes) in the suture group (P<.001). The intensity of the postoperative pain, foreign body sensation, irritation and epiphora were significantly lower in the fibrin glue group than in the suture group (P<.001). Intense itchy sensation at the first 2 postoperative visits was lesser among patients in the fibrin glue group (5 patients, 20%) than in the suture group (12 patients, 48%) (P < .05). Two patients in the fibrin glue group had partial graft dehiscence, these grafts were successfully reattached with fibrin glue. At the end of follow-up, pterygium recurrence was observed in 1 eye (4%) in the fibrin glue group and in 3 eyes (12%) in the suture group (P<.05).

    Conclusion: Using fibrin glue in pterygium surgery with conjunctival autografting significantly reduces surgery time, improves postoperative patient comfort, and results in a lower recurrence rate compared with suturing.

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