Article Text

other Versions

PDF
Treatment of peripapillary choroidal neovascular membranes with intravitreal bevacizumab.
  1. Marta S Figueroa (figueroa{at}servicom2000.com),
  2. Susana Noval (sunoval{at}hotmail.com),
  3. Inés Contreras (inescon3{at}yahoo.com)
  1. Hospital Ramón y Cajal, Spain
  2. Hospital La Paz, Spain
  3. Hospital Ramón y Cajal, Spain

    Abstract

    Aims: To evaluate the effect of intravitreal injections of bevacizumab in the treatment of peripapillary choroidal neovascular membranes.

    Methods: Interventional case series of patients with active peripapillary choroidal neovascular membranes. Ophthalmological examination included best-corrected visual acuity, fundus biomicroscopy, fluorescein angiography and optical coherence tomography (OCT). Bevacizumab injections (1.25 mg) were repeated monthly for the first three months. Re-treatment was considered if there were signs of membrane activity.

    Results: Six eyes of five patients with peripapillary choroidal membranes were included in the study with a mean follow-up of 13 months (range 6 to 16). Bevacizumab was used as the initial treatment in four eyes and to manage recurrences after surgery in the other two. In five eyes three injections of bevacizumab led to a complete resolution of leakage on fluorescein angiography and OCT. In one eye, membrane activity persisted despite six injections of bevacizumab. Visual acuity improved in five eyes with a mean improvement of 4 lines (average: 2-10 lines). It deteriorated only in the eye that did not to respond to treatment.

    Conclusions: The results of this case series suggest that the intravitreal injection of bevacizumab may be an effective treatment for peripapillary choroidal membranes.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.