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Features of Age-Related Macular Degeneration Assessed with 3-Dimensional-Fourier-Domain OCT
  1. Marcel N Menke (marcel.menke{at},
  2. Simeon Dabov (simdabov{at},
  3. Veit Sturm (veit.sturm{at}
  1. University of Zuerich
  2. University of Muenster, School of Medicine
  3. University Hospital of Zurich


    Background/Aims: Age-related macular degeneration (AMD) is amongst the leading causes of severe visual loss in individuals over 60 years old. Retinal changes associated with AMD were previously studied by time-domain optical coherence tomography (OCT). Recently, Fourier-Domain OCT (FD-OCT) has been introduced. FD-OCT provides increased scan resolution, scanning speed and generates 3-dimensional OCT images. The purpose of this study was to demonstrate features of AMD assessed with high-density scanning 3d-FD-OCT (Topcon 3d-OCT1000).

    Methods: The study was designed as a prospective, observational case series. Five patients with typical morphological changes due to AMD were chosen based on funduscopic findings. Eyes with non-exudative- and exudative AMD were included. 3d-FD-OCT images were obtained and typical morphological changes associated with AMD were presented.

    Results: FD-OCT provided detailed 3d-images of retinal structure. In addition, FD-OCT showed improved retinal coverage and image quality. FD-OCT B-scan imaging identified typical retinal changes associated with AMD. In addition, FD-OCT imaging revealed information about the extent and the 3-dimensional shape of retinal lesions.

    Conclusion: 3d-FD-OCT imaging is useful for diagnosing and following patients with AMD. In addition, 3d-FD-OCT provided information about the extent and 3-dimensional shape of retinal pathologies and showed improved retinal coverage.

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