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Blepharo-conjunctivitis due to leishmania (viannia) braziliensis cutaneous infection- Report of two cases in Rio de Janeiro, Brazil
  1. Manoel P Oliveira-Neto (onetohec{at},
  2. Marise Mattos,
  3. Eliezer Benchimol,
  4. Elisa Cupolillo,
  5. Tulia Cuzzi-Maya,
  6. Claude Pirmez,
  7. Gabriel Grimaldi, Jr
  1. Fundação Oswaldo Cruz, Brazil
  2. Fundação Oswaldo Cruz, Brazil
  3. Fundação Oswaldo Cruz, Brazil
  4. Fundação Oswaldo Cruz, Brazil
  5. Fundação Oswaldo Cruz, Brazil
  6. Fundação Oswaldo Cruz, Brazil
  7. Fundação Oswaldo Cruz, Brazil


    The authors report two uncommon cases of chronic granulomatous blepharo-conjunctivitis as a recurrence of Leishmania (Viannia) braziliensis cutaneous leishmaniasis (CL). Patients were otherwise healthy immunocompetent adults, as revealed by a positive cutaneous delayed-type hypersensitivity (DTH) reaction to Leishmania-derived antigens and a typical cell-mediated immunity-induced granulomatous reaction that had effect on the control of parasite replication at the lesions. This rare cause of ocular involvement should be considered in areas where Leishmania is endemic.

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