Article Text

other Versions

PDF
Quantitative Assessment of Lens Opacities with Anterior Segment Optical Coherence Tomography
  1. Amy Lee Wong,
  2. Christopher Kai Shun Leung (tlims00{at}hotmail.com),
  3. Robert Weinreb,
  4. Arthor KC Cheng,
  5. Carol Yim Lui Cheung,
  6. Philip Tze Ho Lam,
  7. Chi-Pui Pang,
  8. Dennis Shun Chiu Lam
  1. The Chinese University of Hong Kong, Hong Kong
  2. The Chinese University of Hong Kong, Hong Kong
  3. UCSD, United States
  4. The Chinese University of Hong Kong, Hong Kong
  5. The Chinese University of Hong Kong, Hong Kong
  6. The Chinese University of Hong Kong, Hong Kong
  7. The Chinese University of Hong Kong, Hong Kong
  8. The Chinese University of Hong Kong, Hong Kong

    Abstract

    Purpose: To evaluate the reliability of lens density measurement with anterior segment optical coherence tomography (OCT) and its association with the Lens Opacity Classification System Version III (LOCS III) grading.

    Methods: Fifty-five eyes from 55 age-related cataract patients were included. One eye from each subject was selected at random for lens evaluation. After dilation, lens photographs were taken with a slit lamp and graded against the LOCS III standardized condition. Anterior segment OCT imaging was performed on the same eyes with high resolution scan. The association between the anterior segment OCT nucleus density measurement and LOCS III nuclear opalescence (NO) and nuclear color (NC) scores was evaluated with Spearman correlation coefficient. Anterior segment OCT measurement precision, coefficient of variation (CVw), and intraclass correlation coefficient (ICC) were calculated.

    Results: The mean NO and NC scores were 3.39+/-1.10 and 3.37+/-1.27, respectively. Significant correlations were found between anterior segment OCT nuclear density measurements and the LOCS III NO and NC scores (r= 0.72 and 0.60, respectively, both with p< 0.001). The precision, CVw and ICC of anterior segment OCT measurement were 2.05 units, 4.55% and 0.98, respectively.

    Conclusion: Anterior segment OCT nucleus density measurement is reliable and correlates with the LOCS III NO and NC scores.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Linked Articles

    • At a glance
      Harminder S Dua Arun D Singh