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Prevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study
  1. Adam K Rudkin (adam{at}rudkin.com.au),
  2. Kapila Edussuriya,
  3. Saman Sennanayake,
  4. Tissa Senaratne,
  5. Dinesh Selva,
  6. Thomas Sullivan,
  7. Robert J Casson
  1. South Australian Institute of Ophthalmology, Adelaide, Australia
  2. Kandy Centre for Save Sight, Sri Lanka
  3. Kandy Centre for Save Sight, Sri Lanka
  4. Kandy Centre for Save Sight, Sri Lanka
  5. South Australian Institute of Ophthalmology, Adelaide, Australia
  6. Department of Statistics and Public Health, Royal Adelaide Hospital, Australia
  7. South Australian Institute of Ophthalmology, Adelaide, Australia

    Abstract

    Aims: To report the prevalence and correlates of exfoliation syndrome (XFS) in central, rural Sri Lanka.

    Methods: A population-based, cross-sectional ophthalmic survey of inhabitants 40 years of age and over from villages in the Kandy District was conducted. Selection was randomized using a cluster sampling process. 1721 eligible participants were identified, 1375 participated. A detailed ophthalmic history and examination including ocular biometry was made of each participant.

    Results: The prevalence of XFS was estimated to be 1.1% (95% CI 0.5-1.5%; 22 eyes). XFS was bilateral in 8 subjects, unilateral in 6 subjects. Univariate analysis demonstrated a significant association between XFS and increasing age (p < 0.001), increasing intra-ocular pressure (odds ratio 1.2; 95% CI 1.09-1.27; p < 0.001), nuclear cataracts (odds ratio 1.92; 95% CI 1.47-2.51; p < 0.001), visual impairment (odds ratio 9.72; 95% CI 3.01-31.44; p < 0.001) and a history of hypertension (odds ratio 3.89; 95% CI 1.14-13.16; p = 0.030).

    Conclusion: XFS in this Sri Lankan population was associated with advanced age, raised intraocular pressure, nuclear cataracts, hypertension and visual impairment.

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