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Br J Ophthalmol doi:10.1136/bjo.2008.141564

Near-Infrared and Short-Wavelength Autofluorescence Imaging in Central Serous Chorioretinopathy

  1. Ali Ayata (ali_ayata{at}yahoo.com),
  2. Sinan Tatlipinar (statlipi{at}yahoo.com),
  3. Taner Kar, Resident (zeytin232003{at}yahoo.com),
  4. Melih Unal (melihu{at}hotmail.com),
  5. Dilaver Ersanli (dilaverersanli{at}yahoo.com.tr),
  6. Ahmet H Bilge
  1. GATA Haydarpaþa Training Hospital, Turkey
  2. Yeditepe School of Medicine, Department of Ophthalmology, Turkey
  3. GATA Haydarpaþa Training Hospital, Turkey
  4. GATA Haydarpaþa Training Hospital, Turkey
  5. GATA Haydarpaþa Training Hospital, Turkey
  6. GATA Haydarpaþa Training Hospital, Turkey
    • Published Online First 1 October 2008

    Abstract

    Purpose: To document short-wavelength (SW) and near-infrared (NIR) autofluorescence properties of acute central serous chorioretinopathy (CSC).

    Methods: Twenty six eyes of the 26 patients diagnosed with CSC (mean age 37.4 years) were included in this retrospective study. Autofluorescence (AF) images were evaluated and compared with angiographic and ophthalmoscopic findings. Fluorescein angiography and AF imaging were performed using a confocal scanning laser ophthalmoscope.

    Results: Focally decreased AF at leakage site was seen in most of the cases with acute CSC (20 of 26 eyes in SW-AF; 20 of 20 eyes in NIR-AF). Twenty four of the 26 cases had the decreased SW-AF corresponding to the area of the serous retinal detachment while 19 of the available 20 cases had the decreased NIR-AF corresponding to the area of the serous retinal detachment. Increased granular AF corresponding to the extent of the former retinal detachment was seen earlier in SW-AF mode, and disappears later in the course of disease with NIR-AF imaging.

    Conclusions: AF imaging of CSC demonstrates different patterns according to the course of the disease reflecting RPE and outer retinal changes. Combining two different AF imaging might predict recent or former CSC episodes and may be a non-invasive technique for monitoring CSC and performing differential diagnosis.

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