Aims: To prospectively examine the recovery of various parameters after discontinuation of overnight orthokeratology.
Methods: Thirty-four eyes of 17 subjects undergoing orthokeratology for 12 months were examined. Refraction, corneal topography, wavefront aberrometry, visual acuity test, and contrast sensitivity test were performed at baseline, 12-month after commencement of the procedure, and 1 week and 1 month after discontinuation of the treatment. Asymmetry and higher order irregularity components were calculated by using Fourier analysis of the corneal topography data. Contrast sensitivity was assessed at four spatial frequencies, and the area under the log contrast sensitivity function (AULCSF) was calculated.
Results: Orthokeratology significantly reduced manifest refraction (P < 0.0001, Dunnett test), and significantly improved uncorrected visual acuity (UCVA) at 12 months after commencement of the procedure (P < 0.0001). Asymmetry and higher order irregularity components significantly increased (P < 0.0001, P = 0.0032, respectively), and third- and fourth-order aberrations also significantly increased (P < 0.0001). The treatment resulted in significant decreases in AULCSF (P = 0.0004).
After discontinuing lens wear, all parameters, such as refraction, UCVA, asymmetry, higher order irregularity, third-order aberration, fourth-order aberration, and AULCSF fully returned to the baseline level within 1 month.
Conclusion: This study confirmed that the effect of orthokeratology is completely reversible in light of optical quality of the eye and quality of vision as well as refraction and visual acuity.
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