Background: To analyze the autofluoresence (AF) properties of pingueculae and compare the size of AF with the extent of the visible lesion.
Methods: Fourty eyes of 23 patients with pingueculae were included into the study. AF images were obtained by using HRA2 confocal scanning laser ophthalmoscope (Heidelberg, Germany); anterior segment photographies were obtained by using TRC-50IX, IMAGEnetTM 2000 Digital Imaging System (Topcon Corp., Japan). The AF characteristics of pingueculae were analyzed. The extent of visible lesion in anterior segment photography and AF image was compared.
Results: AF images revealed well defined hyper-autofluorescence in the area of pinguecula, which was greater than the extent of visible pinguecula in slit-lamp examination, in 40 of 56 lesions (71.4%). In none of the eyes, the hyperautofluorescent area was smaller than the extent of visible lesion.
Conclusion: Pingueculae display hyperautofluorescence in AF imaging. The real size of pingueculae may be estimated by its AF characteristics, which is mostly larger than the visible lesion.