Purpose: To determine whether color or gray scale images from High resolution Spectral OCT are superior in visualizing clinically important details of retinal structures.
Methods: Patients with macular pathologies were imaged using Spectral OCT (OTI Inc, Toronto, Canada). Two reviewers independently analyzed the retinal structures and pathologies and graded them on a 4-point scale on the basis of the visibility. A third reviewer masked to the results then reviewed images where there was a different score for color versus gray scale.
Results: Statistical analysis showed gray scale image to be significantly better in visualizing the details of epiretinal membrane, photoreceptor and RPE layer morphology than color scale image (p =.00088 - 0.0006). In 16.17% of eyes color image led to the false impression of photoreceptor disruption.
Conclusion: Gray scale images are qualitatively superior to the color scale images on High resolution Spectral OCT. Color images can be misleading as the displayed colors are false colors and the observer may see a dramatic change in color and interpret that as a large change in the OCT reflectivity.
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