Purpose: To evaluate vision-related quality of life in persons with branch retinal vein occlusion (BRVO) using the 25-item NEI Visual Function Questionnaire.
Design: Observational, cross-sectional, interviewer-administered study.
Methods: 46 patients with unilateral BRVO were included in this study. Scores on the VFQ-25 were analyzed and converted to scaled scores per NEI VFQ-25 algorithms. Clinical data including age, gender, employment status, living arrangements, visual acuity, number of systemic diseases and duration of BRVO were also recorded. Subscale results were compared to previously published data and subgroup analyses were performed.
Results: Mean adjusted subscale responses amongst BRVO patients were higher (except for ocular pain) than known averages in patients with diabetic retinopathy, central retinal vein occlusion, age-related macular degeneration, and low vision, but lower than known averages in a reference group of people without ocular disease. Subscale responses correlated significantly with visual acuity in the involved eye. This observation held true in 8 of 12 subscales even in patients who maintained vision of 20/25 or better in the uninvolved eye. The General Health subscale and number of systemic diseases correlated significantly with both the General Vision and Peripheral Vision subscale scores. There was no correlation between subscale responses and age.
Conclusions: Branch retinal vein occlusion is a retinal vascular disease that is associated with a decrease in vision-related quality of life as determined by the VFQ-25. A decrease in VFQ-25 score is correlated with involved eye visual acuity, even when good visual acuity is maintained in the uninvolved eye.