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Retinal Imaging Using Commercial Broadband Optical Coherence Tomography
  1. Hitesh Tanna1,
  2. Adam M Dubis2,
  3. Nazia Ayub2,
  4. Diane M Tait2,
  5. Jungtae Rha2,
  6. Kimberly E Stepien2,
  7. Joseph Carroll2,*
  1. 1 Marquette University, United States;
  2. 2 Medical College of Wisconsin, United States
  1. To whom correspondence should be addressed. E-mail: jcarroll{at}mcw.edu

Abstract

Aims: To examine the practical improvement in image quality afforded by a broadband light source in a clinical setting and to define image quality metrics for future use in evaluating spectral domain optical coherence tomography (SD-OCT) images.

Methods: A commercially available SD-OCT system, configured with a standard source as well as an external broadband light source was used to acquire 4mm horizontal line scans of the right eye of 10 normal subjects. Scans were averaged to reduce speckling and multiple retinal layers were analyzed in the resulting images.

Results: For all layers a significant improvement in the mean local contrast was found, (average improvement by a factor of 1.66) when using the broadband light source. Intersession variability is shown not to be a major contributing factor to the observed improvement in image quality obtained with the broadband light source. We report the first observation of sub-lamination within the inner plexiform layer (IPL) visible with SD-OCT.

Conclusion: The practical improvement with the broadband light source was significant, though it remains to be seen what the utility will be for diagnosing pathology. The approach presented here can serve as a model for a more quantitative analysis of SD-OCT images, allowing for more meaningful comparisons between subjects, clinics, and SD-OCT systems.

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