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Filamentous fungi are important aetiological agents of keratitis globally.1 Hyaline hyphomycetes including Fusarium and Aspergillus spp. are most common, but dematiaceous fungi such as Curvularia and Bipolaris spp. constitute approximately 20% of cases.2 3 Commonly reported signs of fungal keratitis include feathery edges, raised lesions, hypopyon, stromal infiltrates and, less frequently, satellite lesions and ring infiltrates.1 In dematiaceous cases, reported characteristics include raised lesions and macroscopic pigmentation.4 5 In this report, we analyse clinical signs of fungal keratitis, comparing hyaline and dematiaceous fungi, and the hyaline fungi Fusarium and Aspergillus spp.
Clinical examination and microbiological reports were collected prospectively in a clinical trial setting. Methods for the trial have been described previously.6 In brief, eligible cases had evidence of filamentous fungus on Gram stain and/or potassium hydroxide. Scrapings were inoculated onto sheep's blood agar, chocolate agar and potato dextrose agar. Fungal cultures were deemed positive with growth on two media or moderate to heavy growth on one media.
After a …