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Brimonidine (Alphagan) associated anterior uveitis
  1. Charlotte M McKnight1,
  2. Josephine C Richards1,
  3. Dru Daniels2,
  4. William H Morgan1
  1. 1Department of Ophthalmology, Royal Perth Hospital, Perth, Western Australia, Australia
  2. 2St John of God Hospital, Subiaco, Western Australia, Australia
  1. Correspondence to Dr Josephine C Richards, Department of Ophthalmology, Royal Perth Hospital, Perth, Western Australia, Australia; diastella{at}iinet.net.au

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Brimonidine is a well-recognised cause of ocular surface disease but is less widely known to cause uveitis. We present important clinical lessons from five new cases of brimonidine-associated anterior uveitis.

Case reports

1. A 64-year-old man with primary open-angle glaucoma presented with red eyes and visual halos. He had used brimonidine 0.2%, timolol 0.5% and bimatoprost 0.03% for 13 months. There was bilateral anterior chamber inflammation with diffuse pigmented and stellate keratic precipitates. His intraocular pressure was 21 mm Hg bilaterally, rising to 26 mm Hg 3 weeks later. A …

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