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I have concerns about the study on Candida fungal keratitis by Matsumoto et al.1 Despite using the word ‘randomised’ in the Methods section, the patients were not randomised at all but merely alternately allocated into each treatment arm. Randomisation implies that participants do not know what each patient will receive. The trial was started in 2001 with the first patient receiving fluconazole yet the text suggests that the second …
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