Reporting outcomes of randomised controlled trials
- Correspondence to Dr Mark R Wilkins, Cornea and External Disease, Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK;
Contributors MRW is the sole contributor to this letter.
- Accepted 27 December 2011
- Published Online First 23 January 2012
I have concerns about the study on Candida fungal keratitis by Matsumoto et al.1 Despite using the word ‘randomised’ in the Methods section, the patients were not randomised at all but merely alternately allocated into each treatment arm. Randomisation implies that participants do not know what each patient will receive. The trial was started in 2001 with the first patient receiving fluconazole yet the text suggests that the second …