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- Published on: 26 February 2013
- Published on: 14 January 2013
- Published on: 26 February 2013Re:Non-inferiority or superiority?Show More
We would like to thank Dr. Geitzenauer for his comments and concerns regarding our study.
As he has pointed out, in a non-inferiority study there is potential for bias which may narrow down the difference in efficacy. Therefore, conducting a superiority study simultaneously would be difficult, unless sufficient quality is ensured during study planning, conduct as well as data analysis.
However, our st...
Conflict of Interest:
None declared. - Published on: 14 January 2013Non-inferiority or superiority?Show More
Dear editors,
Takamura et al. report in a recent edition of the BJO about a "multi- center, randomised, double-masked, parallel study" which leads to both a non-inferiority and a superiority claim of the ophthalmic solution being tested (diquafosol ophthalmic solution).(Reference 1) From a methodological standpoint, the conclusions reached by the authors are not in agreement with current accepted standards in th...
Conflict of Interest:
None declared.