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Emerging concepts in the management of acute retinal necrosis
  1. Robert William Wong1,2,
  2. J Michael Jumper2,
  3. H Richard McDonald2,
  4. Robert N Johnson2,
  5. Arthur Fu2,
  6. Brandon J Lujan2,3,
  7. Emmett T Cunningham Jr2,4
  1. 1Austin Retina Associates, Austin, Texas, USA
  2. 2The Department of Ophthalmology, California Pacific Medical Center, San Francisco, California, USA
  3. 3Department of Vision Science, School of Optometry, University of California, Berkeley, California, USA
  4. 4The Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA
  1. Correspondence to Emmett T Cunningham, Jr, MD, PhD, MPH, West Coast Retina Medical Group, Inc., 185 Berry Street, Lobby 2, Suite 130, San Francisco, CA 94107-1739, USA; emmett_cunningham{at}yahoo.com

Abstract

Acute retinal necrosis (ARN), also known as Kirisawa-type uveitis, is an uncommon condition caused by infection of the retina by one of the herpes family of viruses, most typically varicella zoster virus or herpes simplex virus and less commonly cytomegalovirus. Clinical diagnosis can be challenging and is often aided by PCR-based analysis of ocular fluids. Treatment typically involves extended use of one or more antiviral agents. Long term retinal detachment risk is high. We review the literature on ARN and present an approach to the diagnosis and management of this serious condition.

  • Infection
  • Inflammation

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