Article Text

other Versions

PDF
Letter
Antibacterial effect of human milk for common causes of paediatric conjunctivitis
  1. Justin T L Baynham1,
  2. M Allison Moorman2,
  3. Catherine Donnellan3,
  4. Vicky Cevallos3,
  5. Jeremy D Keenan1,3
  1. 1Department of Ophthalmology, University of California, San Francisco, California, USA
  2. 2Department of Pediatrics, University of California, San Francisco, California, USA
  3. 3Francis I. Proctor Foundation, University of California, San Francisco, California, USA
  1. Correspondence to Dr Jeremy D Keenan, Francis I Proctor Foundation, University of California, 513 Parnassus Avenue, Box 0412, San Francisco, CA 94143-0412, USA; jeremy.keenan{at}ucsf.edu

Statistics from Altmetric.com

Introduction

The use of human milk in the treatment of ocular surface disease is documented in ancient Egyptian, Indian, Greek, Roman and Byzantine texts.1 Galen recommended human milk specifically for conjunctivitis.1 Ocular application of human milk continues today in the developing world, and is recommended in widely distributed parenting guidebooks. Despite these endorsements, the antibacterial activity of topically applied breast milk has not been adequately studied. In this report, we assess the inhibitory effects of human breast milk against common ocular pathogens.

Methods

Mothers attending routine outpatient paediatric visits at the University of California, San Francisco, donated milk samples for this study. Subjects with known immunodeficiency, systemic infection or antibiotic use within 2 weeks were excluded. Milk samples were stored at 4°C; the samples were tested within 6 h of collection, or frozen for later testing.

We tested several reference strains of bacteria from the American Type Culture Collection (ATCC): …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.