Article Text

other Versions

PDF
Ocular adnexal IgG4-related disease: CT and MRI  findings
  1. Yong Sub Song1,
  2. Ho-Kyung Choung2,3,
  3. Sun-Won Park1,4,
  4. Ji-Hoon Kim1,
  5. Sang In Khwarg3,
  6. Yoon Kyung Jeon5
  1. 1Department of Radiology, Seoul National University College of Medicine, Seoul, Korea
  2. 2Department of Ophthalmology, Boramae Medical Center, Seoul, Korea
  3. 3Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
  4. 4Department of Radiology, Boramae Medical Center, Seoul, Korea
  5. 5Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
  1. Correspondence to Dr Sun-Won Park, Department of Radiology, Boramae Medical Center, 5-Gil 20, Boramae-Road, Dongjak-gu, Seoul 156-707, Korea; Department of Radiology, Seoul National University College of Medicine, Seoul, Korea; swpark8802{at}gmail.com

Abstract

Background/aims To evaluate CT and MRI findings of histopathologically proven ocular adnexa IgG4-related disease.

Methods Study subjects included 18 patients with histopathologically proven ocular adnexal IgG4-related disease. CT (n=16) and MR (n=3) images were retrospectively evaluated for location, laterality, shape, margin, attenuation on precontrast CT images, T1 and T2 signal intensity on precontrast MRI , internal architecture, ocular adnexal lesion enhancement patterns, sialadenitis of major salivary glands, cervical lymph node enlargement and perilesional bony change.

Results Lacrimal gland enlargement was observed in 16 cases. Extraglandular lesions were observed in the medial canthus (n=2) and extraconal space (n=2). Bilateral supraorbital and infraorbital nerves, pterygopalatine fossa and cavernous sinus involvement were observed in one case. All ocular adnexal lesions showed well defined margins, isoattenuation on precontrast CT images, isointensity on T1- and hypointensity on T2-weighted images, homogenous internal arcithecture and enhancement patterns and bone remodelling without destruction.

Conclusions Ocular adnexal IgG4-related disease can involve the lacrimal gland, medial canthus, extraconal space, supraorbital and infraorbital nerves, pterygopalatine fossa and cavernous sinus. A diagnosis of ocular adnexal IgG4-related disease should be considered in lesions with the typical imaging features described herein.

  • Anatomy
  • Eye Lids
  • Imaging
  • Lacrimal gland
  • Inflammation

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.