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Efficacy of split hours part-time patching versus continuous hours part-time patching for treatment of anisometropic amblyopia in children: a pilot study
  1. Virender Sachdeva1,
  2. Vaibhev Mittal1,
  3. Ramesh Kekunnaya2,
  4. Amit Gupta2,
  5. Harsha L Rao3,
  6. Joseph Mollah4,
  7. Anand Sontha5,
  8. Rekha Gunturu5,
  9. B Venkateshwar Rao6
  1. 1Department of Pediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Nimmagada Prasad Children's Eye Care Centre, L V Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India
  2. 2Department of Pediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Jasti V Ramanamma Children's Eye Care Centre, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India
  3. 3Centre for Clinical Epidemiology and Biostatistics, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India
  4. 4Department of Optomtery, Jasti V Ramanamma Children's Eye Care Centre, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India
  5. 5Department of Optometry, Nimmagada Prasad Children's Eye Care Centre, L V Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India
  6. 6Shreya Eye Care Centre, Hyderabad, Andhra Pradesh, India
  1. Correspondence to Dr Ramesh Kekunnaya, Head, Pediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Jasti V Ramanamma Children's Eye Care Centre, L V Prasad Eye Institute, KAR Campus, Hyderabad, Andhra Pradesh 500034, India; rameshak{at}lvpei.org, drrk123{at}gmail.com

Abstract

Aim To compare efficacy of ‘split hours part-time patching’ and ‘continuous hours part-time patching’ for the treatment of anisometropic amblyopia.

Methods We designed a prospective, interventional, non-randomised, comparative pilot study involving children between 4 and 11 years of age with anisometropic amblyopia who were treated with either continuous wear (Group A) or split hours part-time patching (Group B) as per parents wish, after appropriate discussion with the parents. Children were followed-up for the improvement in visual acuity and the compliance at each follow-up visit.

Results 44 and 24 children were recruited in Group A and Group B, respectively (mean±SD baseline BCVA of the amblyopic eye: 0.99±0.32 and 0.95±0.23 logMAR, respectively). BCVA (adjusted for baseline BCVA and age) at 3 months in Group A (0.59±0.24) was comparable (p=0.08) with that in Group B (0.71±0.24). This was same even at 6 months (0.51±0.25 in Group A and 0.59±0.25 in Group B, p=0.25). The improvement in BCVA at 3 months was also comparable (p=0.06) in Group A (0.39±0.23) and Group B (0.26±0.23). The improvement in BCVA at 6 months was also comparable (p=0.14) in Group A (0.47±0.26) and Group B (0.37±0.26).

Conclusions Both patching regimens lead to significant and comparable improvement in BCVA in anisometropic amblyopia up to 6 months of follow-up.

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