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We describe the cases of a 15-year-old girl and her father. She first presented at the age of 9 to Southampton University Hospital Ophthalmology department with recurrent attacks of iritis and corneal infiltrate denser in the left eye compared to the right (figure 1). Her past medical history suggested that her condition started in the neonatal period when her immunisations were missed as she developed a rash at 8 weeks. She regularly experienced rashes and high fevers with some episodes requiring hospital admission.
At the ocular inflammatory stage of her condition, rheumatological assessment revealed tenderness in her feet, ankles and knees, and combined with the ophthalmic presentation, a diagnosis of juvenile idiopathic arthritis was made. MRI and ultrasound scans showed no evidence of synovitis. The severity of her arthritis was related to the exacerbations of her ocular features. The patient's inflammatory markers were all negative. She was managed with NSAIDS (naproxen) with mild relief.
Since the age …