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  1. San-Ni Chen1,2,
  2. Iebin Lian3,4
  1. 1Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan
  2. 2School of Medicine, Chung Shan Medical University, Taichung, Taiwan
  3. 3Graduate Institute of Statistics and Information Science, National Changhua University of Education, Changhua, Taiwan
  4. 4Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
  1. Correspondence to Dr San-Ni Chen, Department of Ophthalmology, Changhua Christian Hospital, No.135, Nanhsiao St., Changhua City 500, Taiwan; 108562{at}cch.org.tw

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We appreciate the comment and questions from Drs Huising and McGwin, which help us with the opportunity to further clarify the relationship between central serous chorioretinopathy (CSCR) and coronary heart disease (CHD).

In our study,1 the stratified Cox proportional hazard analysis showed that patients with CSCR are at higher risk of developing CHD; however, the conditional logistic regression analysis of CSCR status on CHD did not reveal that CHD is a risk factor for CSCR. It seems a …

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