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Innovations
Minor ipsilateral simple limbal epithelial transplantation (mini-SLET) for pterygium treatment
  1. Erick Hernández-Bogantes1,
  2. Guillermo Amescua2,
  3. Alejandro Navas1,
  4. Yonathan Garfias3,4,
  5. Arturo Ramirez-Miranda1,
  6. Alejandro Lichtinger1,
  7. Enrique O Graue-Hernández1
    1. 1Department of Cornea and Refractive Surgery, Instituto de Oftalmologia, Fundacion Conde de Valenciana, México, D.F, México
    2. 2Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA
    3. 3Research Unit, Instituto de Oftalmología, Fundación Conde de Valenciana, México, D.F, México
    4. 4Department of Biochemistry, Faculty of Medicine, UNAM, México, D.F, México
    1. Correspondence to Dr Enrique O. Graue-Hernández, Chimalpopoca 14, Col. Obrera, Deleg. Cuauhtémoc, Ciudad de México, 06800, México; egraueh{at}gmail.com

    Abstract

    We describe a novel surgical technique for pterygium removal taking advantage of the properties of amniotic membrane and limbal epithelial stem cells. A total of 10 eyes underwent pterygium excision with amniotic membrane coverage of the bare sclera and placement of pieces of limbal epithelium in a linear fashion in the affected limbal area covered by a second amniotic membrane using fibrin glue. After up to 8 months of follow-up, there were no signs of early recurrence or sight-threatening complications. The minor ipsilateral simple limbal epithelial transplantation technique for the treatment of pterygium requires less tissue than the conventional conjunctival autograft, leaving healthy conjunctiva if needed for another procedure in the future and offers the advantages of epithelial stem cells, which in the long term may reduce the rate of recurrence significantly.

    • Cornea
    • Conjunctiva
    • Stem Cells

    This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

    https://doi.org/10.1136/bjophthalmol-2015-306857

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