eLetters

47 e-Letters

published between 2011 and 2014

  • Perceptual learning in visual acuity and contrast sensitivity: continuous improvement or discovery effect?
    Michael Bach

    In their paper "Repetitive tests of visual function improved visual acuity in young subjects" Otto and Michelson [1] assessed effects of practice on visual acuity, using the Freiburg Visual Acuity Test "FrACT" developed by one of us [2,3]. At first glance they seem to confirm our findings [4], which showed a marked increase of visual acuity after visual training, more than 0.1 logMAR. At closer inspection, discrepancies...

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  • Reproducibility of aberrometry-based intraoperative refraction during cataract surgery, Statistical issues
    Siamak Sabour

    We were interested to read the paper by Huelle JO and colleagues published in the May 2014 issue of BJO. The authors aimed to provide the first clinical data in determining the feasibility, quality and precision of intraoperative wavefront aberrometry (IWA)-based refraction in patients with cataract. Precision (reproducibility) and measurement quality was evaluated by the 'limits of agreement' approach, regression analysi...

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  • FRACTURED OZURDEX IMPLANT DURING THE PROCEDURE
    Gonzaga Garay-Aramburu

    In the recent article published in British Journal of Ophthalmology, Agrawal et al1

    reported two cases of desegmentation of Ozurdex implant in vitreous cavity. In this report, the authors comment that Allergan confirmed that fractured implants in the applicator have not been found to date during the quality control process. We recently reported2

    also two cases of implant fragmentation in response t...

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  • Is the term dry eye a misnomer?
    W LESLIE ALEXANDER

    As an ophthalmologist for many years, I continue to find the diagnosis of dry eye difficult unless it is severe. I have spoken to colleagues who have the same experience. As detailed in this paper there are many things going on in the pathophysiology of which dryness may be one. Can I suggest it might be helpful to our understanding and approach to sore eyes, to be less dogmatic about attributing dryness as the reason f...

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  • Significant design flaws bias the results in favour of aflibercept
    Andrew Zambanini

    Dr Cho and colleagues present data on a very small cohort of patients with wet AMD that have switched treatment from either bevacizumab or ranibizumab to aflibercept. Of note, this subgroup comprised approximately 8% of the total number of patients switched to aflibercept.

    Any retrospective review is likely to be heavily biased by the anticipated 'treatment benefit' of a new therapy particularly if, as in this ca...

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  • The long-term psychosocial impact of correction surgery for adults with strabismus
    Gerald McGwin

    We read with interest Jackson and Morris's response to our letter.

    The author's indicated that it was not possible to conduct a repeated measures ANOVA using SPSS. However, SPSS provides several ways to analyze repeated measures ANOVA through the general linear model command. There are several excellent texts that illustrate how to conduct an ANOVA using a repeated measures design in the SPSS environment....

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  • Re:Non-inferiority or superiority?
    Etsuko Takamura

    We would like to thank Dr. Geitzenauer for his comments and concerns regarding our study.

    As he has pointed out, in a non-inferiority study there is potential for bias which may narrow down the difference in efficacy. Therefore, conducting a superiority study simultaneously would be difficult, unless sufficient quality is ensured during study planning, conduct as well as data analysis.

    However, our st...

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  • Non-inferiority or superiority?
    Wolfgang Geitzenauer

    Dear editors,

    Takamura et al. report in a recent edition of the BJO about a "multi- center, randomised, double-masked, parallel study" which leads to both a non-inferiority and a superiority claim of the ophthalmic solution being tested (diquafosol ophthalmic solution).(Reference 1) From a methodological standpoint, the conclusions reached by the authors are not in agreement with current accepted standards in th...

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  • Risk of cataract for patients with diabetes mellitus
    Tomoyuki Kawada

    I read the paper entitled "Risk of selected eye diseases in people admitted to hospital for hypertension or diabetes mellitus: record linkage studies" with interest. It elucidated that diabetes mellitus has a risk of several ocular diseases with significance using two big epidemiological data. However, I have two queries on their outcome by selecting the association between cataract and diabetes mellitus.

    First,...

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  • Improving access to eye care in a remote region in Western Kenya
    Rebecca Nightingale

    Using a chart review, Nyamori and colleagues estimated the incidence of retinoblastoma in Kenya to be 1:17,000 live births, similar to global estimates.1 They observed that late presentation was common, often attributed to poor awareness or socioeconomic barriers which hinder access to care. We describe a recent project to improve access to eye care for people living in Western Kenya.

    IcFEM Dreamland Mission Hos...

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