eLetters

190 e-Letters

published between 2005 and 2008

  • We are part of the problem
    Andrew Bastawrous

    Dear Editor

    We read with great interest the report by Raftery et al on Ranibizumab (Lucentis) versus bevacizumab (Avastin): modelling cost effectiveness. The authors raise the very pertinent point in respect to a single company owning two competing drugs and the inherent cost to tax payers. The authors conclude their abstract with "Public pressure may be the most potent weapon in persuading Genentech to license bevaciz...

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  • Bevicizumab detection
    Rajesh K Sharma

    Dear Editor,

    We appreciated the paper by Iriyama et al.[1] The authors have investigated the role of anti vascular endothelial growth factor (VEGF) antibodies on retinal ganglion cells in rats. It is an interesting and relevant paper considering the clinical use of anti-VEGF antibodies in a variety of ocular conditions.[2] However, there are a couple of issues that require further clarification.

    The author...

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  • Sudden lowering of IOP may cause posterior segment bleeding by three different mechanisms
    Atul Bansal

    Dear Editor,

    We read with great interest the report by Alwitry et al [1] on severe decompression retinopathy after medical treatment of acute angle closure. The authors have speculated that the mechanism of the ‘preretinal’ haemorrhage in this case was similar to the scattered ‘intraretinal’ haemorrhages seen in ocular decompression retinopathy. Although we agree with them that the haemorrhage was caused by sudd...

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  • Natural killer T cells in chronic uveitis
    Jae Kyoun Ahn

    Dear Editor

    I read with interest the article by Pedroza-Seres M and associates who assessed the pathogenic roles of peripheral CD57+ natural killer T (NKT) cell in pars planitis.[1] The authors compared the frequencies of CD57+ NKT cell in peripheral blood between pars planitis patients and healthy controls, and then evaluated the effector-related surface molecules and functions of CD57+ NKT cells derived from pa...

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  • Treatment of peripapillary choroidal neovascularisation
    Laurence POSTELMANS

    Dear Editor

    We read with interest the article by Aisenbrey et al [1] who have described the results of surgical treatment of peripapillary choroidal neovascularisation in eight patients.

    As reported, peripapillary choroidal neovascularisation is a relatively uncommon entity that can be a variant of macular choroidal neovascularisation in elderly patients. Accordingly to the MPSG[2], early small peripapilla...

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  • Alcohol delamination of the corneal epithelium for recalcitrant recurrent corneal erosion syndrome:
    Lawrence W Hirst

    Dear Editor

    I commend the authors for yet another treatment for this potentially disabling and common affliction. I note that one important component of this treatment requires the mapping of the site of the erosion during an attack with this area being singled out for the localised 4-6mm of treatment. However, in most patients that I have treated over the years the area of erosion is healed by the time they seek...

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  • Authors' response: Mechanism of action of bimatoprost.
    Louis B. Cantor

    Dear Editor,

    We thank Dr. Camras for his interest in our report on levels of bimatoprost and its free acid in the aqueous humour of cataract patients after a single topical dose of bimatoprost [1] and welcome the opportunity to respond to his comments. We are in agreement with Dr. Camras that the results of our study [1] and those of his previously reported study [2] are similar, showing low nanomolar concentrat...

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  • Authors' reply: Vitamin A deficiency during pregnancy and congenital microphthalmos
    Christian E Decock

    Dear Editor,

    We would like to thank the authors Hornby and Gilbert for their interesting letter referring to our case report of bilateral colobomatous microphthalmos with orbital cyst.[1] Their remarks and view are relevant and demand further clarification.

    Because our intention was to investigate more in depth the origin of the cyst fluid and wall and because of space limitations, we were not able to...

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  • Intraocular pressure rise during dilatation
    Nathan M. Radcliffe

    Dear Editor

    We read with great interest a recent report by Siam et al., “The amount of intraocular pressure rise during pharmacological pupillary dilatation is an indicator of the likelihood of future progression of glaucoma.” These authors report that the likelihood of optic nerve progression (defined by the disc damage likelihood scale, the glaucoma staging system 2, or both) in open angle patients is related t...

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  • Bevacizumab for polypoidal vasculopathy should be evaluated in a cross cultural population
    Shree K Kurup

    Dear Editors

    We read with great interest, the illuminating article by Drs Gomi, Sawa and Tano. Our limited experience (4 Afro-American patients) with intravitreal bevacizumab (IVB) for polypoidal vasculopathy (PPV) has been more positive.

    We had reported the first success early this year in terms of lasting remission [1]. Furthermore, I enclose details on another patient who had PPV OU, in all likeliho...

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