eLetters

190 e-Letters

published between 2005 and 2008

  • Cost effectiveness of cataract surgery
    Ediriweera Desapriya

    Dear Editor

    According to the Canadian Community Health Survey, approximately 82% of the population of seniors aged 65 – 80+ (3,000,000 seniors) reported having vision problems in Canada. [1] Cataracts are the leading cause of vision impairment among seniors. Between the period of 1994 – 2003, proportions of seniors with cataracts rose from 14% – 20% with populations aged 75 and over accounting for higher percentage...

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  • Tobacco alcohol amblyopia - Authors reply
    Raed Behbehani

    Dear Editor

    We appreciate the comments of Grzybowski et al. about our article. We agree that the term "tobacco alcohol amblyopia" is not very accurate and does not specifically describe the underlying cause of vision loss. It may also not fit the "historic" description of the condition. However, the term is still used widely to describe a spectrum characterized by optic nerve dysfunction and selective involvement of...

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  • Cataract surgery in England
    Simon P Kelly

    Dear Editor

    We read with interest the paper by Keenan [ref 1] and colleagues.

    We recently studied the 2005/06 Hospital Episode Statistics (HES) data for cataract and have reached similar conclusions. We agree with the authors’ observations that as NHS cataract surgery rates (CSRs) in England have increased significantly in recent years, several questions are now raised. What is the appropriate CSR in a d...

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  • Use of Avastin in rat models: Comments.
    Yuksel Totan

    Dear Editor

    We have read Manzano et al’s insightful paper[1] with interest and appreciated the comments concerning the inhibitory effects of bevacizumab on corneal neovascularisation (NV). However, the manuscript had some important aspects that need to be clarified. Cumulative data from numerous basic and clinical studies strongly implicates the central role of VEGF in ocular and corneal angiogenesis. Binding all free-ci...

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  • Vitamin A deficiency and possible link with colobomatous malformations
    Stella J Hornby

    Dear Editor

    We read with interest the letter by Decock et al regarding the rare congenital ocular malformation (orbital cyst and bilateral colobomatous microphthalmos). [1]

    The female child reported was the product of a mother with documented vitamin A deficiency (VAD) during the second trimester of pregnancy after previous gastric bypass surgery for morbid obesity. The authors do not report the sympto...

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  • Was it really tobacco alcohol-amblyopia ?
    Andrzej Grzybowski

    Dear Editor,

    Further to the article of Behbehani R, Sergott RC and Savino PJ Tobacco-alcohol amblyopia: a maculopathy? [1], we question whether either patient had tobacco-alcohol amblyopia (TAA).

    “TAA” occurs in patients with high alcohol and tobacco intake, but is perhaps a misnomer with “nutritional optic neuropathy” being more appropriate. Many such patients are nutritionally deficient consequent u...

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  • Bimatoprost, the prodrug of a prostaglandin analog
    Carl B Camras

    Dear Editor,

    We congratulate the authors of their adequately designed study(1) that demonstrates the high concentration of the free acid (the product of hydrolysis) of bimatoprost (BP), an amide, in the aqueous humor of patients receiving a single drop of BP 1, 3, or 6 hours prior to cataract surgery. This important study confirms the results found in previous studies.(2,3) However, despite providing important confirmat...

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  • Bevacizumab and rodent VEGF
    Jing Hua

    Dear Editor,

    We read with interest the recently published paper by Manzano et al. titled ‘Inhibition of experimental corneal neovascularisation by bevacizumab (Avastin)’. The authors used topical eyedrop application of either saline or bevacizumab in a rat model of corneal neovascularization, with apparent moderate success. Furthermore, in their discussion, they mention that there was incomplete inhibition of th...

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  • Avastin effect on the optic nerve
    Sherif AK Amer

    Dear Editor

    The rising use of Avastin injection for choroidal neovascular membranes and other conditions has been successful in preliminary reports. However, I have experienced 5 cases with optic neuropathy following Avastin injection after an interval of 2-4 months. Although my number of cases is very small, it suggests that a study be conducted to investigate the effect of intravitreal Avastin on the optic nerve u...

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  • Retinal and subdural haemorrhages from minor falls?
    Horace B Gardner

    Dear Editor

    I wish to thank Ganesh et al for confirming (p <0.001) the marked and obvious difference between the age distribution of retinal and subdural haemorrhages in America and Japan. Finding this difference "not surprising" neither negates nor explains it. More sophisticated child abuse teams could not discover cases in Japan months before they occur. Variations in incidence of osteogenesis imperfecta wou...

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