Original articlePosterior Capsule Opacification in the Presence of an Intraocular Lens with a Sharp versus Rounded Optic Edge
Section snippets
Patients
All patients who were admitted consecutively to the Hayashi Eye Hospital for bilateral cataract surgery between October 2001 and March 2002 were screened by a clinical research coordinator. Exclusion criteria were ocular pathologic features other than senile cataract, history of prior ocular surgery or inflammation, eyes scheduled for planned extracapsular cataract extraction with nucleus expression, a pupil diameter less than 6.0 mm after full dilation, patients with diabetes mellitus, and
Results
The participant flow in this study is shown in Figure 2. Because the surgical procedures were the same for the 2 IOLs, patients were not aware of the type of IOL implanted. The surgeon and examiners also were unaware of the type of IOL used because the 2 IOLs are similar in appearance. Furthermore, because the controller of this clinical trial kept concealed the assignment schedule until the end of the study, the data analyst, who was also the surgeon, did not know the type of IOL used. During
Discussion
Our study demonstrated that the degree of PCO in eyes that received an acrylic IOL with a sharp posterior optic edge did not progress, whereas PCO in eyes that received a rounded-edge acrylic IOL showed a marginal (albeit statistically significant) increase. Consequently, the degree of PCO associated with a sharp-edge IOL was significantly less than that with a rounded-edge IOL. Furthermore, the incidence of Nd:YAG laser posterior capsulotomy was significantly less in eyes with the sharp-edge
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Manuscript no. 2005-45.
The authors have no proprietary interest in any of the materials mentioned in the article and have received no financial support.