Original articleComparison of Retinal Nerve Fiber Layer Thickness Measured by Cirrus HD and Stratus Optical Coherence Tomography
Section snippets
Subjects
All study subjects were recruited prospectively in a consecutive manner from the glaucoma clinic and examined between March 2008 and August 2008 at the Asan Medical Center, Seoul, Korea. At the initial evaluation, all subjects underwent a complete ophthalmologic examination including medical, ocular, and family history; visual acuity testing; Humphrey field analyzer (HFA) Swedish Interactive Threshold Algorithm 24-2 full-threshold test (Car Zeiss Meditec, Inc); multiple intraocular pressure
Results
Among the 163 participants, 75 were women, 88 were men, and all were Asian. Among 163 eyes, 55 eyes had glaucoma, 48 were GS subjects, and 60 were healthy subjects. The mean ± standard deviation age of each group was 53.7±10.9, 53.3±11.3, and 51.3±12.6 years, respectively. The average mean deviation of each group was −5.91±5.68 dB, −0.85±1.48 dB, and −0.67±1.48 dB, respectively. The VF outcomes and OCT measurements of the glaucoma, GS subjects, and healthy groups are summarized in Table 1. Both
Discussion
With the use of both technologies, significant structural differences were observed among healthy eyes, GS eyes, and glaucomatous eye in our series. This finding is consistent with previous studies,3, 18 which reported RNFL thickness measured with scanning laser polarimetry or OCT to be significantly lower in glaucomatous subjects compared with GS subjects. The ability to detect differences between GS eyes and glaucomatous eyes with Cirrus HD-OCT as in our series may reflect its usefulness as a
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Manuscript no. 2008-1201.
Financial Disclosure(s): The authors have no commercial or proprietary interest in any of the materials discussed in this article.