Factors that correlate with improvement in vision after combined Intacs and trans-epithelial corneal crosslinking

Br J Ophthalmol. 2010 Dec;94(12):1597-601. doi: 10.1136/bjo.2010.182691. Epub 2010 Aug 30.

Abstract

Aim: To analyse factors that correlate with best corrected visual acuity (BCVA) improvement after Intacs and trans-epithelial corneal collagen crosslinking with riboflavin-carboxymethylcellulose.

Methods: A 3-year retrospective study of 14 eyes that underwent trans-epithelial crosslinking and same day Intacs.

Results: The mean preoperative BCVA and spherical equivalent were significantly related to BCVA postoperatively.

Conclusion: Poorer preoperative BCVA and spherical equivalent were associated with greater improvement in postoperative BCVA.

MeSH terms

  • Adolescent
  • Adult
  • Carboxymethylcellulose Sodium
  • Collagen / metabolism*
  • Cornea / physiopathology*
  • Cornea / surgery
  • Corneal Topography
  • Epithelium, Corneal / drug effects
  • Epithelium, Corneal / physiopathology*
  • Epithelium, Corneal / surgery
  • Female
  • Humans
  • Keratoconus / drug therapy
  • Keratoconus / physiopathology*
  • Keratoconus / therapy*
  • Male
  • Middle Aged
  • Photosensitizing Agents / therapeutic use*
  • Retrospective Studies
  • Riboflavin / therapeutic use*
  • Treatment Outcome
  • Ultraviolet Rays
  • Visual Acuity / physiology
  • Young Adult

Substances

  • Photosensitizing Agents
  • Collagen
  • Carboxymethylcellulose Sodium
  • Riboflavin