TY - JOUR T1 - Azithromycin for ocular toxoplasmosis JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 1306 LP - 1308 DO - 10.1136/bjo.82.11.1306 VL - 82 IS - 11 AU - Aniki Rothova AU - Lotje E H Bosch-Driessen AU - Ninette H van Loon AU - W Frits Treffers Y1 - 1998/11/01 UR - http://bjo.bmj.com/content/82/11/1306.abstract N2 - AIMS To investigate the efficacy of azithromycin in patients with ocular toxoplasmosis. METHODS 11 immunocompetent patients with ocular toxoplasmosis were treated with azithromycin (500 mg the first day, followed by 250 mg/day for 5 weeks). Ocular and systemic examinations were performed during active retinitis episodes and all patients were followed for at least 1 year. RESULTS The intraocular inflammation disappeared within 4 weeks in seven patients, including two cases with progressive retinitis despite previous treatment with pyrimethamine, sulphadiazine, and folinic acid. Recurrence of retinitis occurred in three patients (27%) within the first year of follow up. No systemic side effects of azithromycin were encountered. CONCLUSION These results indicate that although azithromycin cannot prevent recurrent disease it may be an effective alternative for patients with ocular toxoplasmosis who cannot tolerate standard therapies. ER -