PT - JOURNAL ARTICLE AU - R Tadayoni AU - A Gaudric AU - B Haouchine AU - P Massin TI - Relationship between macular hole size and the potential benefit of internal limiting membrane peeling AID - 10.1136/bjo.2006.091777 DP - 2006 Oct 01 TA - British Journal of Ophthalmology PG - 1239--1241 VI - 90 IP - 10 4099 - http://bjo.bmj.com/content/90/10/1239.short 4100 - http://bjo.bmj.com/content/90/10/1239.full SO - Br J Ophthalmol2006 Oct 01; 90 AB - Aim: To investigate the relationship between the size of macular holes and the possible benefit of internal limiting membrane (ILM) peeling. Methods: 84 consecutive cases of idiopathic macular hole followed up for at least 3 months were included in this retrospective study. Surgery comprised pars plana vitrectomy, peeling of any epiretinal membrane, 17% C2F6 (hexafluoroethane) gas filling and 10 days of positioning. 36 eyes had ILM peeling. The main outcome measure was the macular hole closure rate checked by optical coherence tomography. Results: The overall postoperative closure rate was 90.5%. For macular holes ⩾400 μm in diameter, the rate was 100% with ILM peeling versus 73.3% without (p = 0.015). For smaller macular holes, the rates were 100% in both groups. Postoperative gain in visual acuity was not significantly different in eyes with ILM peeling and those without. Conclusions: ILM peeling does not seem to be useful for macular hole <400 μm in diameter. Its likely benefit has to be investigated for larger macular hole sizes, for which the failure rate is higher.