TY - JOUR T1 - Comparison of choroidal thicknesses using swept source and spectral domain optical coherence tomography in diseased and normal eyes JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 354 LP - 358 DO - 10.1136/bjophthalmol-2014-305331 VL - 99 IS - 3 AU - Colin S H Tan AU - Wei Kiong Ngo AU - Kai Xiong Cheong Y1 - 2015/03/01 UR - http://bjo.bmj.com/content/99/3/354.abstract N2 - Background/aims Choroidal thickness measurements are reported to differ between swept source optical coherence tomography (SS-OCT) and spectral domain OCT (SD-OCT). This study aimed to assess the comparability of choroidal thickness measurements using SS-OCT and SD-OCT devices among patients with retinal diseases and normal participants. Methods In a prospective cohort study of 100 subjects, comprising patients with retinal disease and normal volunteers, OCT scans were performed sequentially with the DRI OCT-1 and Spectralis OCT using standardised imaging protocols. Subfoveal choroidal thicknesses were independently measured by masked reading-centre certified graders. Paired t tests and intraclass correlation coefficients (ICCs) were used to compare the measurements. Results Among all 100 participants, mean subfoveal choroidal thickness was 264.3 µm and 272.4 µm for DRI OCT-1 and Spectralis OCT respectively (p=0.001), with ICC of 0.989. The mean difference in choroidal thickness between OCT devices was larger among eyes with retinal diseases compared with normal eyes (8.4 µm vs 7.3 µm). Eyes with choroidal thickness ≤200 µm had smaller differences between OCT devices compared with those with thicker choroids (mean 3.6 µm vs 10.0 µm, p=0.021). Conclusions Subfoveal choroidal thickness measurements are comparable between DRI OCT-1 and Spectralis OCT. The presence of retinal disease increases the variability of choroidal thickness measurements between OCT devices. ER -