TY - JOUR T1 - Myopic choroidal neovascularisation: current concepts and update on clinical management JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 289 LP - 296 DO - 10.1136/bjophthalmol-2014-305131 VL - 99 IS - 3 AU - Tien Y Wong AU - Kyoko Ohno-Matsui AU - Nicolas Leveziel AU - Frank G Holz AU - Timothy Y Lai AU - Hyeong Gon Yu AU - Paolo Lanzetta AU - Youxin Chen AU - Adnan Tufail Y1 - 2015/03/01 UR - http://bjo.bmj.com/content/99/3/289.abstract N2 - Choroidal neovascularisation (CNV) is a common vision-threatening complication of myopia and pathological myopia. Despite significant advances in understanding the epidemiology, pathogenesis and natural history of myopic CNV, there is no standard definition of myopic CNV and its relationship to axial length and other myopic degenerative changes. Several treatments are available to ophthalmologists, but with the advent of new therapies there is a need for further consensus and clinical management recommendations. Verteporfin photodynamic therapy has been an established treatment for subfoveal myopic CNV for many years, but this treatment does not restore visual acuity and is associated with long-term chorioretinal atrophy. More recently, clinical trials investigating the efficacy and safety of anti-vascular endothelial growth factor agents in patients with myopic CNV have demonstrated substantial visual acuity gains and quality of life increases compared with photodynamic therapy. These enhanced outcomes provide updated evidence-based clinical management guidelines of myopic CNV, and increase the need for a generally accepted definition for myopic CNV. This review critically summarises the latest myopic CNV literature in the context of clinical experience and recommends a myopic CNV treatment algorithm. ER -