PT  - JOURNAL ARTICLE
AU  - Takuji Kato
AU  - Kiyoo Nakayasu
AU  - Yuji Hosoda
AU  - Yasuo Watanabe
AU  - Atsushi Kanai
TI  - Corneal wound healing following laser in situ keratomileusis (LASIK): a histopathological study in rabbits
AID  - 10.1136/bjo.83.11.1302
DP  - 1999 Nov 01
TA  - British Journal of Ophthalmology
PG  - 1302--1305
VI  - 83
IP  - 11
4099  - http://bjo.bmj.com/content/83/11/1302.short
4100  - http://bjo.bmj.com/content/83/11/1302.full
SO  - Br J Ophthalmol1999 Nov 01; 83
AB  - AIMS To investigate the histopathological changes of rabbit corneas after laser in situ keratomileusis (LASIK) and to evaluate the corneal wound healing process. METHODS A LASIK was performed on white rabbit eyes. Postoperatively, rabbits were killed on days 1 and 7, and at 1, 3, and 9 months. RESULTS Periodic acid Schiff (PAS) positive material and disorganised collagen fibre were seen along the interface of the corneal flap even 9 months after operation. CONCLUSIONS The wound healing process still continued at 9 months after LASIK indicating that a much longer time than expected was required for corneal wound healing following LASIK.