PT  - JOURNAL ARTICLE
AU  - Sing-Pey Chow
AU  - Cathy L Hopkinson
AU  - Derek M Tole
AU  - Mark N Jones
AU  - Stuart D Cook
AU  - W John Armitage
TI  - Stability of visual outcome between 2 and 5 years following corneal transplantation in the UK
AID  - 10.1136/bjophthalmol-2016-310129
DP  - 2017 Jun 09
TA  - British Journal of Ophthalmology
PG  - bjophthalmol-2016-310129
4099  - http://bjo.bmj.com/content/early/2017/06/08/bjophthalmol-2016-310129.short
4100  - http://bjo.bmj.com/content/early/2017/06/08/bjophthalmol-2016-310129.full
AB  - Background and Aims Many studies of corneal transplantation focus on graft failure or rejection as endpoints, or report visual outcomes at one postoperative time point. We aimed to study the stability of visual outcomes between 2 and 5 years following corneal transplantation.Methods All patients with keratoconus (868) or Fuchs endothelial dystrophy (FED) (569) receiving their first corneal transplant for visual purposes in the UK between January 2003 and December 2009 were included. The probability of visual improvement or deterioration (gain or loss of ≥2 Snellen lines, respectively) between 2 and 5 years after keratoplasty was modelled by multivariable logistic regression.Results The majority of keratoconus patients with a penetrating keratoplasty (PK) or deep anterior lamellar keratoplasty maintained their visual acuity (651/868; 75%) while 15% (133/868) improved and 10% (84/868) deteriorated. Similarly, most patients with FED who received a PK maintained their vision (395/569; 70%) while 18% (105/569) improved and 12% (68/569) deteriorated.