PT  - JOURNAL ARTICLE
AU  - Jin Ma
AU  - Honghui Li
AU  - Xiaohu Ding
AU  - Silvia Tanumiharjo
AU  - Lin Lu
TI  - Effectiveness of combined macular buckle under direct vision and vitrectomy with ILM peeling in refractory macular hole retinal detachment with extreme high axial myopia: a 24-month comparative study
AID  - 10.1136/bjophthalmol-2016-310123
DP  - 2017 Oct 01
TA  - British Journal of Ophthalmology
PG  - 1386--1394
VI  - 101
IP  - 10
4099  - http://bjo.bmj.com/content/101/10/1386.short
4100  - http://bjo.bmj.com/content/101/10/1386.full
SO  - Br J Ophthalmol2017 Oct 01; 101
AB  - Purpose To evaluate the efficacy of a combined macular buckle under direct vision and 23-gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling in refractory macular hole retinal detachment (MHRD) with extreme high axial myopia.Design Prospective, randomised controlled study.Participants The study included 98 eyes of 98 patients of MHRD with extreme high axial (>30 mm) myopia.Intervention Patients were randomly assigned to undergo PPV with ILM peeling (group 1, n=52) or PPV with ILM peeling combined with macular buckle under direct vision (group 2, n=46).Main outcome measures Complete ocular examination included best-corrected visual acuity (BCVA) (LogMAR), applanation tonometry, optical biometry, slit-lamp biomicroscopy, colour fundus photography, ultrasound examination and optical coherence tomography at baseline and every follow-up visit.Results Initial retinal reattachment rate was significantly higher in group 2 than in group 1 at 12-month postoperatively (χ2 test, p=0.020). Macular hole closure rate in group 2 was significantly higher than that in group 1 at 3, 12, 18 and 24 months postoperatively (Fisher's exact test, p<0.05). In initial retinal reattachment cases, the mean BCVA decreased significantly in group 2 than in group 1 at 3 months postoperatively (Wilcoxon matched pairs signed rank test, p=0.036), and had increased significantly in group 2 than in group 1 since 6 months postoperatively (Wilcoxon matched pairs signed rank test, p<0.05). Mean axial lengths in group 2 were significantly shorter than that of group 1 at each follow-up time point (Wilcoxon matched pairs signed rank test, p<0.05).Conclusions Combined macular buckle under direct vision and PPV with ILM peeling is more effective in treatment of MHRD with extreme high axial (>30 mm) myopia.