Number of immune cells in VKC and control specimens (mean (SD))
| Cell type | Control (n=4) | VKC (n=14) | p Value |
|---|---|---|---|
| ICAM-1 (CD54) | 0 | 34.7 (9.6) | — |
| ICAM-3 (CD50) | 19.0 (4.7) | 76.4 (11.4) | < 0.0001 |
| LFA-1 α chain (CD11a) | 15.0 (2.6) | 87.9 (13.1) | < 0.0001 |
| LFA-1 β chain (CD18) | 14.8 (1.7) | 90.5 (24.9) | < 0.0001 |
| VLA-4 (CD49D) | 3.8 (1.7) | 21.6 (7.2) | 0.0001 |
| HLA-DR | 17.3 (2.2) | 75.3 (13.0) | < 0.0001 |
| T helper/inducer cells (OKT4-Leu3a) | 14.5 (4.7) | 43.7 (13.9) | 0.0004 |
| T cytotoxic/suppressor cells (OKT8) | 14.3 (3.9) | 16.2 (5.8) | 0.27 (NS) |
| B cells (L26) | 17.8 (7.8) | 32.6 (17.0) | 0.059 (NS) |
| Macrophages (KP1) | 19.3 (4.3) | 27.9 (8.9) | 0.04 |
VKC = vernal keratoconjunctivitis; ICAM-1 = intercellular adhesion molecule-1; ICAM-3 = intercellular adhesion molecule-3; LFA = lymphocyte function antigen-1; VLA-4 = very late activation antigen-4.
NS = not significant.