Renal and ocular features of patients with thin basement membrane disease (TBMD)
| Patient | Sex | Age (years) | FH | Haem | Protein | BP | Cornea | Lens | Retina |
|---|---|---|---|---|---|---|---|---|---|
| IM | F | 49 | − | 180 | 1.6 | + | Pigment | N | Retinal pigment epithelial clumping maculopathy 15 dots |
| IdS | F | 63 | − | >500 | 0.2 | + | Arcus, corneal dystrophy | Cataract | 2 dots |
| RB | F | 30 | − | 63 | 0.1 | N | N | N | 7.5 dots |
| OM | F | 30 | + | 100 | 1.34 | N | Dots | N | 4 dots |
| JH | M | 54 | − | >500 | 0.5 | + | N | Dots | 0 dots |
| DC | F | 37 | − | 10 | 0.86 | N | Dots | N | 3.5 dots |
| RB | F | 35 | + | 100 | 0.3 | N | N | N | 8 dots |
| AM | F | 51 | − | 100 | 0.2 | N | Dots | N | 3 dots |
| RL | F | 48 | − | 10 | 0.1 | N | N | N | 4.5 dots |
| GK | F | 36 | − | 40 | 0.1 | N | Dots | Dots | 6 dots |
| ML | F | 49 | − | 90 | 0.1 | + | Arcus | N | 5.5 dots |
| RH | F | 44 | − | 12 | 0.1 | N | N | Dots | 2 dots |
| DH | F | 36 | − | 100 | 0.3 | N | N | N | 8 dots |
| IC | F | 59 | − | 20 | 0.4 | + | Dots, arcus | N | 5.5 dots |
| MB | F | 60 | + | 48 | 0.1 | N | N | N | 10 dots |
| JK | F | 52 | + | 74 | 0.3 | N | Corneal dystrophy | N | 0.5 dots |
| MD | F | 41 | − | micro | 1.38 | N | N | N | 3 dots |
N = normal; FH = family history of TBMD; Haem = number of RBC × 106/l; micro=microscopic haematuria; proteinuria in g/24 hours; BP + = blood pressure greater than 140/90 mm Hg; retinal dot counts are given as mean number per individual (left + right eye ÷ 2).