Patient profiles of treatment responsive and treatment non-responsive dry eyes
| Responsive | Non-responsive | p Value | |
|---|---|---|---|
| Age (years) | 52.4 (15.0) | 48.9 (14.3) | 0.118 |
| Sex (M:F) | 43:254 | 24:25 | 0.000 |
| Tear function: | |||
| Break up time (s) | 3.9 (2.8) | 3.4 (1.9) | 0.631 |
| Schirmer-I test (mm) | 6.9 (6.5) | 8.9 (8.2) | 0.045 |
| Tear clearance (X) | 16.7 (18.1) | 14.1 (11.5) | 0.823 |
| Tear function index | 114.3 (224.8) | 110.1 (138.8) | 0.121 |
| Nasal stimulation (mm) | 18.6 (14.2) | 26.6 (15.9) | 0.007 |
| Ocular surface conditions: | |||
| Rose bengal score | 2.8 (2.8) | 1.2 (1.2) | 0.000 |
| Fluorescein score | 2.2 (2.3) | 1.3 (1.4) | 0.018 |
| Systemic conditions: | |||
| ANA (>160) | 48/297 | 1/49 | 0.016 |
| RA (>160) | 43/297 | 1/49 | 0.029 |
| SS-A | 44/297 | 1/49 | 0.026 |
| SS-B | 11/297 | 0/49 | 0.353 |
Each value shows average (SD). p Value was calculated by Mann–Whitney U test or χ2 test.