Table 7

Bleb related infection after trabeculectomy with or without antiproliferatives

Author	Year	Antiproliferatives	No of cases	No of eyes	Incidence (%)
Freedman	1978	none	2	133	1.5
Mills	1981	none	2	435	0.45
Shirato	1982	none	1	113	0.9
Katz	1985	none	2	1100	0.2
Wolner	1991	5-FU	13	229	5.7
			4^†	133	3.0
			9^‡	96	9.4
Ticho	1993	5-FU	4	105	3.8
			2^†	88	2.3
			2^‡	17	11.8
Higginbotham	1996	MMC	6	229	2.6
			2^†	179	1.1
			4^‡	50	8.0
Greenfield	1996	MMC	13	609	2.1
Present study	1997	none	1	76	1.3
			1^†	74	1.4
			0^‡	2	0
		5-FU	3	228	1.3
			3^†	210	1.4
			0^‡	18	0
		MMC	7	662	1.1
			5^†	612	0.8
			2^‡	50	4.0

↵Number of trabeculectomies; ^†superiorly located blebs;^‡inferiorly located blebs; 5-FU = 5-fluorouracil; MMC = mitomycin C.