Levels (SD) of plasminogen and total vitreal protein in the vitreous and plasminogen/protein ratios in normal controls and in vitreoretinal disorders. Plasminogen was measured enzymatically as described in Methods
| Plasminogen (mg/ml) | Total protein (mg/ml) | Correlation | Ratio plasminogen/ total protein | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| r | p Value | ||||||||||||
| Control | 0.016 (0.005) | 0.85 (0.36) | 0.92 | 0.001 | 0.019 | ||||||||
| Macular pucker | 0.027 (0.012) | * | 1.37 (0.65) | ns | 0.79 | 0.048 | 0.020 | ||||||
| Idiopathic PVR | 0.108 (0.039) | ** | 8.24 (1.86) | ** | 0.81 | 0.009 | 0.013 | ||||||
| Traumatic PVR | 0.109 (0.040) | ** | 8.87 (3.91) | ** | 0.73 | 0.015 | 0.012 | ||||||
| PDR (diabetes type I) | 0.079 (0.041) | ** | 3.25 (0.97) | ** | 0.68 | 0.039 | 0.024 | ||||||
| PDR (diabetes type II) | 0.112 (0.031) | ** | 3.94 (1.12) | ** | 0.73 | 0.036 | 0.028 | ||||||
| PDR (diabetes type II + insulin) | 0.174 (0.054) | ** | 8.57 (2.98) | ** | 0.84 | 0.018 | 0.020 | ||||||
Vitreal protein was determined using the Lowry method.20 Ratios were derived from these data (* = 0.02/** p < 0.01 by Mann-Whitney U test compared with control vitreous).