Table 3

Clinical efficacy

	Day 10			Day 28			Day 42			Day 56
	LOD	NG		LOD	NG		LOD	NG		LOD	NG
Investigator’s opinion:
Missing	0	2		3	5		6	4		10	12
Cure	0	1		2	2		3	0		8	0
Satisfactory response	14	4		14	9		13	10		7	10
Slight improvement	15	12		9	6		7	11		4	8
Unchanged	7	13		8	12		7	8		5	7
Slightly worse	0	5		0	2		0	3		2	0
Significantly worse	0	0		0	1		0	1		0	0
Total	36	37		36	37		36	37		36	37
p Value	0.002			0.088			0.036			0.14

Patient’s opinion:
Missing	0	2		3	5		6	4		10	12
Cure	0	1		2	3		3	0		8	1
Satisfactory response	19	7		21	9		14	10		8	11
Slight improvement	12	10		5	9		6	11		6	4
Unchanged	5	13		5	8		7	7		3	9
Slightly worse	0	4		0	1		0	3		1	0
Significantly worse	0	0		0	2		0	2		0	0

Total	36	37		36	37		36	37		36	37
p Value	0.001			0.026			0.021			0.055

LOD = lodoxamide, NG = NAAGA.