Percentage change in cell count (with 95% confidence interval) from day 0 to day 14
| Thiotepa | |||
|---|---|---|---|
| 5 minutes % change (95% CI) | 30 minutes % change (95% CI) | ||
| (A) Concentration of thiotepa (mg/ml): | |||
| Control | 103 (87 to 119) | 83 (64 to 102) | |
| 0.06 | 44 (31 to 58) | 42 (26 to 58) | |
| 0.12 | 30 (9 to 51) | 11 (−3 to 25) | |
| 0.25 | 21 (5 to 36) | 3 (−9 to 16) | |
| 1.00 | 24 (8 to 40) | 5 (−8 to 18) | |
| 4.00 | 9 (−15 to 30) | −9 (−15 to −3) | |
| 5-FU | |||
| 5 minutes % change (95% CI) | 30 minutes % change (95% CI) | ||
| (B) Concentration of 5-FU (mg/ml): | |||
| Control | 106 (83 to 130) | 74 (52 to 97) | |
| 0.06 | 9 (0 to 17) | 6 (0 to 12) | |
| 0.12 | 3 (−1 to 8) | 2 (−10 to 14) | |
| 0.25 | −2 (−10 to 6) | 3 (−2 to 8) | |
| 1.00 | −2 (−13 to 8) | −1 (−6 to 4) | |
| 4.00 | 0 (−16 to 17) | −8 (−17 to 0) | |
See Table 3 (C and D) for significance of results.