Values (mean (SD)) for the arteriovenous passage time, the arterial mean dye bolus velocity, and the diameter of the temporal arteries before and after application of the test drug
| Arteriovenous passage time (s) | Arterial mean dye bolus velocity (mm/s) | Arterial diameter (μm) | ||||||
|---|---|---|---|---|---|---|---|---|
| Before | After | Before | After | Before | After | |||
| Topical placebo | 1.57 (0.3) | 1.58 (0.3) | 6.42 (1.0) | 6.26 (1.1) | 105 (14) | 106 (14) | ||
| Topical metipranolol | 1.68 (0.4) | 1.47 (0.3) | 5.97 (1.4) | 6.70 (1.0) | 106 (15) | 107 (16) | ||
| Systemic placebo | 1.56 (0.3) | 1.45 (0.3) | 6.34 (1.3) | 6.81 (1.2) | 106 (15) | 107 (13) | ||
| Systemic metipranolol | 1.62 (0.5) | 1.44 (0.4) | 6.28 (1.5) | 6.90 (1.2) | 108 (14) | 106 (15) | ||
↵Significant differences between the measurements before and after application of the test drug; p<0.05; Student’st test.