Biochemical variables in hereditary vascular retinopathy (HVR) patients, relatives, and healthy controls
| Variables | Controls (n=19) | HVR patients (n=12) | Relatives (n=9) | One way ANOVA | |||||
|---|---|---|---|---|---|---|---|---|---|
| p value | F ratio | ||||||||
| Plasma 5-HT (nmol/l) | 9.8 (2.8) | 5.6 (1.4) | 5.1 (1.1) | <0.0001 | 20.91 | ||||
| Platelet 5-HT (nmol/109platelets) | 3.2 (0.6) | 2.2 (0.8) | 2.0 (0.9)† | 0.0001 | 11.84 | ||||
| Plasma tryptophan (μmol/l) | 51 (8) | 42 (6)† | 45 (6) | 0.0024 | 7.11 | ||||
| Tryptophan ratio | 8.7 (0.9) | 7.7 (1.1)‡ | 7.8 (1.0) | 0.0138 | 4.82 | ||||
Data are presented as mean (SD).
↵Significantly different from control group (p<0.001); †Significantly different from control group (p<0.01); ‡Significantly different from control group (p<0.05; Bonferroni test).