Table 4

Randomised prospective multicentre study on tPA in cases with fibrin formation after cataract surgery

(A) Presence of fibrin
Days after treatment		tPA (n=44)		Standard therapy (n=41)		Statistical significance
Any intraocular fibrin:
Before therapy		100%		100%		ns
1		59.1%		95.1%		p=0.001
2		59%		90.3%		p=0.001
14		11.4%		29.3%		p=0.039
90		0%		2.4%		ns
Anterior chamber fibrin:
Before therapy		84.1%		85.4%		ns
1		45.5%		80.5%		p=0.0009
2		43.2%		78.0%		p=0.001
14		2.3%		9.8%		ns
90		0%		0%		ns
IOL surface fibrin:
Before therapy		97.7%		92.7%		ns
1		nd		nd		nd
2		47.7%		80.5%		p=0.000067
14		9.1%		24.4%		p=0.05
90		0%		2.4%		ns
(B) Rate of intraocular fibrin 1 and 14 days after treatment
Days after treatment		tPA (n=44)			Standard therapy (n=41)
Days after treatment		1	14		90	1	14	90
None	40.9%	93.2%	100%	4.9%	75.6%	97.6%
Mild	31.8%	6.8%	0%	46.3%	24.4%	2.4%
Moderate	25%	0%	0%	39%	0%	0%
Severe	2.3%	0%	0%	9.8%	0%	0%