Crude and adjusted odds ratios (right eyes) for failing the City University Tritan Test in rural communities in an onchocercal area, northern Nigeria, according to two criteria. Variables investigating factors toxic to optic nerve and ocular disease
| Variable under comparison | Relative odds of failing screening plates (95% CI) | Relative odds of failing grading plates (95% CI) | ||||
|---|---|---|---|---|---|---|
| Crude odds ratio | Adjusted odds ratio | Crude odds ratio | Adjusted odds ratio | |||
| Alcohol: | ||||||
| Never | 1.00 | 1.00 | 1.00 | 1.00 | ||
| Drink past/present | 2.48 (2.00–3.08) | 1.39 (0.99–1.96) | 2.94 (1.90–4.55) | 0.90 (0.46–1.77) | ||
| Diethylcarbamazine: | ||||||
| Never | 1.00 | 1.00 | 1.00 | 1.00 | ||
| Yes | 3.08 (2.48–3.82) | 1.07 (0.80–1.44) | 4.86 (3.21–7.36) | 1.14 (0.66–1.96) | ||
| Skin snip: | ||||||
| Negative | 1.00 | 1.00 | 1.00 | 1.00 | ||
| Microfilaria positive | 2.59 (2.09–3.21) | 1.22 (0.90–1.65) | 4.64 (2.89–7.44) | 1.14 (0.62–2.10) | ||
| Visual acuity: | ||||||
| 6/9 | 1.00 | 1.00 | 1.00 | 1.00 | ||
| 6/18–6/60 | 13.8 (10.5–18.2) | 3.35 (2.29–4.90) | 29.4 (19.1–45.4) | 7.88 (4.35–14.3) | ||
| Diagnosis of cataract | ||||||
| None | 1.00 | 1.00 | 1.00 | 1.00 | ||
| Yes | 11.1(7.61–16.1) | 1.63 (0.95–2.80) | 10.17(5.60–18.5) | 1.27 (0.52–3.08) | ||
| Diagnosis, optic nerve disease | ||||||
| None | 1.00 | 1.00 | 1.00 | 1.00 | ||
| Optic atrophy | 9.68 (7.34–12.8) | 3.55 (2.48–5.08) | 24.1 (15.7–37.2) | 5.30 (2.97–9.45) | ||
| Glaucoma | 29.0 (10.7–78.4) | 15.9 (4.22–60.2) | 46.8 (14.6–150) | 8.87 (1.61–48.7) | ||
Adjustment for sex, age, ethnic group, education, occupation, religion, alcohol, and diethylcarbamazine consumption, microfilarial load, visual acuity, and diagnosis of cataract and optic nerve disease. Results from right eyes only presented, since there was no statistical difference from the left eye results.